Genetic and Genomic Facility

The UQDI is home to the UQ Centre for Clinical Genomics, the most sophisticated and largest human genomic facility in the southern hemisphere. The Centre undertakes cutting-edge genetics and genomics studies including:

· whole genome or exome-sequencing to map monogenic diseases

· gene-mapping in common diseases

· RNA sequencing for genomic profiling

The research capability of the UQ Centre for Clinical Genomics is unrivalled in Australia. It houses state-of-the-art sequencing infrastructure including GAII and HiSeq 2000 sequencers managed by a strong team of geneticists and bioinformaticians. The Centre provides an extremely valuable resource for the Australian genetics community and provides training and career development opportunities for young researchers who would otherwise have to seek career opportunities overseas.

The UQDI is well-equipped for genetic and genomic studies including SNP genotyping, DNA sequencing, gene-expression profiling. Key equipment includes an Illumina microarray genotyping facility for genome-wide association study level genotyping and gene-expression array studies. Technology for smaller scale genotyping projects also exists, including an AB7900 HT and OpenArray facility, enabling single marker and moderate multiplex TaqM SNP genotyping. Sequencing equipment includes an AB3100 capillary sequencer, and an Illumina Genome Analyzer sequencer, which is used for high throughput DNA sequencing, and a range of other sequencing-based applications including ChIP-Sq, and RNA-Sq transcriptom profiling.

For further information, please contact the Institute Director at di.director@uq.edu.au